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Diabetes and eye disease

Definition

Diabetes can harm the eyes. It can damage the small blood vessels in the retina, the back part of your eye. This condition is called diabetic retinopathy.

Diabetes also increases the chance of having glaucoma, cataracts, and other eye problems.

Alternative Names

Retinopathy - diabetic; Photocoagulation - retina; Diabetic retinopathy

Causes

Diabetic retinopathy is caused by damage from diabetes to blood vessels of the retina. The retina is the layer of tissue at the back of the inner eye. It changes light and images that enter the eye into nerve signals, which are sent to the brain.

Diabetic retinopathy is a main cause of blindness in Americans 20 to 74 years old. People with type 1 or type 2 diabetes are at risk of this condition.

Diabetes - retinal conditions

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Diabetes - retinal conditions

There are two stages of diabetic retinopathy:

  • Nonproliferative develops first
  • Proliferative is more advanced and severe

The chance of getting retinopathy and having a more severe form is higher when:

  • You have had diabetes for a long time
  • Your blood sugar (glucose) has been poorly controlled

Other eye problems that can develop in persons with diabetes include:

  • Cataract -- cloudiness of the eye lens
  • Glaucoma -- increased pressure in the eye that can lead to blindness
  • Macular edema -- blurry vision due to fluid leaking into the area of the retina that provides sharp central vision
  • Retinal detachment -- scarring that may cause part of the retina to pull away from the back of your eyeball

Symptoms

Most often, diabetic retinopathy has no symptoms until the damage to your eyes is severe.

Symptoms of diabetic retinopathy include:

  • Blurred vision and slow vision loss over time
  • Floaters
  • Shadows or missing areas of vision
  • Trouble seeing at night

Many people with early diabetic retinopathy have no symptoms before bleeding occurs in the eye. This is why everyone with diabetes should have regular eye exams.

Exams and Tests

Your eye doctor (ophthalmologist) will examine your eyes. You may first be asked to read an eye chart. Then you will receive eyedrops to widen the pupils of your eyes. Tests you may have involve:

Measuring the fluid pressure inside your eyes (tonometry)

Checking the structures inside your eyes (slit lamp exam)

Checking and photographing your retinas (fluorescein angiography)

If you have the early stage of diabetic retinopathy (nonproliferative), the eye doctor may see:

  • Blood vessels in the eye that are larger in certain spots (called microaneurysms)
  • Blood vessels that are blocked
  • Small amounts of bleeding (retinal hemorrhages) and fluid leaking into the retina

If you have advanced retinopathy (proliferative), the eye doctor may see:

  • New blood vessels starting to grow in the eye that are weak and can bleed
  • Small scars forming on the retina and in other parts of the eye (the vitreous)

Treatment

Persons with early diabetic retinopathy may not need treatment. But they should be closely followed by an eye doctor who is trained to treat diabetic eye diseases.

Once your eye doctor notices new blood vessels growing in your retina (neovascularization) or you develop macular edema, treatment is usually needed.

Eye surgery is the main treatment for diabetic retinopathy.

Laser eye surgery creates small burns in the retina where there are abnormal blood vessels. This process is called photocoagulation. It is used to keep vessels from leaking or to shrink abnormal vessels.

Surgery called vitrectomy is used when there is bleeding (hemorrhage) into the eye. It may also be used to repair retinal detachment.

Medicines that are injected into the eyeball may help prevent abnormal blood vessels from growing.

Follow your eye doctor's advice on how to protect your vision. Have eye exams as often as recommended.

Support Groups

American Diabetes Association | www.diabetes.org

National Diabetes Information Clearinghouse | www.diabetes.niddk.nih.gov

Prevent Blindness America | www.preventblindness.org

Outlook (Prognosis)

Managing your diabetes may help slow diabetic retinopathy and other eye problems. Control your blood sugar (glucose) level by:

  • Eating healthy foods
  • Getting regular exercise
  • Checking it as often as instructed by your diabetes health care provider and keeping a record of your numbers so you know the things that affect your level
  • Taking medicine or insulin as instructed

Treatments can reduce vision loss. They do not cure diabetic retinopathy or reverse the changes that have already occurred.

Possible Complications

Diabetic eye disease can lead to reduced vision and blindness.

When to Contact a Medical Professional

Call for an appointment with an eye doctor (ophthalmologist) if you have diabetes and you have not seen an ophthalmologist in the past year.

Call your doctor if any of the following symptoms are new or are becoming worse:

  • You cannot see well in dim light.
  • You have blind spots.
  • You have double vision (you see two things when there is only one).
  • Your vision is hazy or blurry and you cannot focus.
  • You have pain in one of your eyes.
  • You are having headaches.
  • You see spots floating in your eyes.
  • You cannot see things on the side of your field of vision.
  • You see shadows.

Prevention

Tight control of blood sugar, blood pressure, and cholesterol is very important for preventing diabetic retinopathy.

Do not smoke. If you need help quitting, ask your doctor or nurse.

References

American Diabetes Association. Standards of medical care in diabetes -- 2013. Diabetes Care. 2013;36 Suppl 1:S11-S66.

Brownlee M, Aiello LP, Cooper ME, et al. Complications of diabetes mellitus. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM. Williams Textbook of Endocrinology. 12th ed. Philadelphia, Pa.: Elsevier Saunders; 2011: chap 33.

Rosenblatt BJ, Benson WE. Diabetic retinopathy. In: Yanoff M, Duker JS, Augsburger JJ, eds. Ophthalmology. 3rd ed. Philadelphia, Pa.: Elsevier Mosby; 2008:chap 6.19.


Review Date: 5/28/2013
Reviewed By: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.
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